• In the present study we found

  2021-01-09

  

  In the present study, we found that the up-regulatory effects of androgens on ep1 transcripts might be mediated by Arα in the olfactory rosette of B. sinensis. However, in mammals, there is no evidence of AR expression in either the vomeronasal organ or the sensory epithelium of main olfactory epith

• br Results br Discussion It has been thought that

  2021-01-09

  

  Results Discussion It has been thought that commitment to the plasma cell fate begins while Torin 2 receptor are still in the GC (Suan et al., 2017, Victora and Nussenzweig, 2012), but the main obstacle to test this model and, if correct, to clarify how the plasma cell-prone GC cells develop

• Caspase-8 Colorimetric Assay Kit br General Characteristics

  2021-01-08

  

  General Characteristics of the Type II Dehydrogenases Alternative NAD(P)H dehydrogenases conduct the reaction of the rotenone-insensitive oxidation of cytosolic and mitochondrial matrix NADH and/or NADPH (Fig. 1) (Melo et al., 2004, Rasmusson et al., 2004, Rasmusson et al., 2008). They catalyze t

• By stratifying EOC cell lines according to their

  2021-01-08

  

  By stratifying EOC cell lines according to their EMT stages, we observed a significant higher expression of DDR1 in the epithelial-like cell lines compared to low or undetectable DDR1 in mesenchymal-like cell lines. Similar trend was observed in the tumour samples, with the lowest expression of DDR1

• Water solubility experimental data of

  2021-01-08

  

  Water solubility experimental data of 24 water + hydrocarbon mixtures are used to find a general correlation for CPA model parameters. Finally, the model is benchmarked against three complex water solubility data set (Athabasca bitumen + water mixtures) from the literature [25], [26]. The model reli

• Coumarins also known as benzopyran ones are a family of

  2021-01-08

  

  Coumarins also known as benzopyran-2-ones are a family of nature-occurring lactones first isolated from Tonka beans in 1820. They are an important class of oxygen containing heterocycles widely found in nature, so much so that they have been routinely employed as herbal remedies since early days. Ov

• br Results with scrubbing process Based on the

  2021-01-08

  

  Results with scrubbing process Based on (S)-Methylisothiourea sulfate discussion of Section 4.4 and area availability results of the previous section, scrubbing process, at the pixel processing rate, was included to mitigate error accumulation on the arrays and on the line-buffer. Eight sequentia

• Although further experiments are needed

  2021-01-08

  

  Although further experiments are needed to determine definitively whether D–ETB receptor heterodimers exist, for example, by using fluorescence resonance Dynorphin A mg transfer analysis or co-immunoprecipitation of receptors, the results of the study by Zeng and colleagues appear to indicate that

• Immune modulation by steroid hormones is a

  2021-01-08

  

  Immune modulation by steroid hormones is a rather new aspect of the research on endocrine interactions in lower vertebrates (Harris and Bird, 2000). In the classical view, steroids exert their effects by binding to specific intracellular receptors that function as ligand-activated transcriptional re

• In the present study it

  2021-01-08

  

  In the present study, it was particularly of interest that intravesical administration of PGE2 evoked ONO-8130-reversible rapid phosphorylation of ERK in the L6 spinal cord. Detection of phosphorylated ERK is now often used as a marker for somatic and visceral nociception, including lxr synthesis p

• br Materials and methods br Results br Discussion

  2021-01-08

  

  Materials and methods Results Discussion Studies have suggested that the Hh signaling pathway, which plays as an essential autocrine viability factor for MFBs [10], [11], is a potential therapeutic target for liver fibrosis. Previously reported works have proven the effectiveness of the Hh

• Similarly in the EAE model Chalmin et

  2021-01-08

  

  Similarly in the EAE model, Chalmin et al. previously demonstrated that EBI2 and CH25H might be responsible for the efficient egress of differentiated Th17 cells from the draining lymph nodes [31]. As discussed above, in active EAE we did not find differences in EAE development and only the transfer

• br Introduction O Methylguanine DNA methyltransferase MGMT

  2021-01-08

  

  Introduction O6-Methylguanine-DNA methyltransferase (MGMT) is a DNA-repair enzyme that specifically transfers alkyl adducts from the O6 position of guanine to the cysteine residue (Cys145) in its active site. In cancer cells, this ability of MGMT disrupts the cytotoxic actions of alkylating antic

• Our results indicate a deregulation of DNA methylation machi

  2021-01-08

  

  Our results indicate a deregulation of DNA methylation machinery during seed development in apomixis. Since DRM2 is targeted loci through an RNA-directed DNA methylation (RdDM) pathway involving 24-nt siRNAs (Stroud et al., 2014, Law and Jacobsen, 2010) and differentially expressed between apomict a

• Examination of Wnt signaling via for example complexes of fr

  2021-01-08

  

  Examination of Wnt signaling via, for example, complexes of frizzled (Fz) and lipoprotein-receptor-related protein (LRP) receptors has been hindered by difficulties in producing Wnt ligands due to their inherent hydrophobicity [20]. This bottleneck was recently bypassed by constructing highly solubl

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