• Our results add to previously published data

  2024-06-24

  

  Our results add to previously published data on the contribution of ALDH3A1 to the optical properties of the cornea. Specifically, the study by Nees et al. (2002) was among the first to examine whether ALDH3A1 serves as a structural component in the cornea and similarly to lens crystallins. Their ex

• Tissue distribution showed that ctrp was abundantly expresse

  2024-06-24

  

  Tissue distribution showed that ctrp9 was abundantly expressed in the kidney of male and female tilapia. In mice, the Ctrp9 was identified in adipose tissue, and the expression levels were higher in females than that of males (Wong et al., 2009). Recent studies indicated that Ctrp9 was also expresse

• HT modulates cortical and hippocampal pyramidal cell

  2024-06-24

  

  5-HT modulates cortical and hippocampal pyramidal cell function in a very complex manner, since most 5-HT receptor subtypes (excitatory as well as inhibitory) are expressed on pyramidal SB743921 as well as GABAergic interneurons that exert inhibitory control over pyramidal cells (Leiser et al., 201

• Tension within the network could be explained by two

  2024-06-24

  

  Tension within the network could be explained by two potential mechanisms: the more classical contractility that is dependent on motor proteins that are pulling AXL1717 filaments towards each other [10]; or contractility that is caused by disassembly of a crosslinked network of actin filaments [2].

• Plant material and growth conditions Arabidopsis

  2024-06-24

  

  Plant material and growth conditions. Arabidopsis thaliana ecotype Columbia was grown on a mixture of soil, vermiculite, and perlite (4:2:1) with a 16h light/8h dark Bay 65-1942 HCl salt in a temperature-controlled growth room (22°C), unless indicated otherwise. Molecular cloning and plant transfor

• Most studies on d penicillamine induced MG were

  2024-06-24

  

  Most studies on d-penicillamine-induced MG were performed before the discovery that some MG patients have anti-MuSK antibodies. After the identification of the present case, we retrospectively tested the stored frozen sera of ten earlier identified d-penicillamine MG patients with anti-AChR Chromoca

• br Introduction Fungi are an inexhaustible

  2024-06-24

  

  Introduction Fungi are an inexhaustible source of natural products mainly due to their wide distribution in the nature, estimated to range from 1.5 to 5.1 million species in the world [1]. Secondary metabolites from fungi represent a substantial fraction of drugs and drug models in pharmaceutical

• br Materials and methods br

  2024-06-24

  

  Materials and methods Results Discussion The brain is endowed with the 5-LOX enzymatic system (Lammers et al., 1996, Lindgren et al., 1984), but its physiological and pathological roles are still not clear. Inflammation is a characteristic of many neurodegenerative diseases such as Alzheime

• The present work has implications for our thinking about

  2024-06-24

  

  The present work has implications for our thinking about the effects of antidepressant (e.g. SSRIs) use on maternal care in depressed mothers which consist of approximately 10–20% of all mothers (Gjerdingen and Yawn, 2007, Susser et al., 2016), and more than 40% of depressed mothers are prescribed w

• Signaling through Axl can lead

  2024-06-24

  

  Signaling through Axl can lead to activation of the PI3K/Akt and Ras/MAPK pathways which promote cellular phenotypes (e.g., transformation, migration) consistent with pro-survival and pro-metastatic effects., , Inhibition of Axl activity by a variety of approaches (including pharmacologic, dominant

• br Conclusions In the current study we found that the

  2024-06-22

  

  Conclusions In the current study, we found that the exposure of maduramicin to chicken myocardial Suramin hexasodium salt results in cellular damage and even death via the induction of apoptosis. Maduramicin upregulated the expression of apoptotic genes and activated caspase cascades, which were

• To better illustrate the involved neuronal postganglionic

  2024-06-22

  

  To better illustrate the involved neuronal postganglionic pathways, central apelin-13 injection was performed in rats received peripheral preadministration of NOS inhibitor L-NAME, sympatholytic agent guanethidine and/or muscarinic receptor agonist bethanechol. Compared with the rats received vehicl

• The putative residue apelin proprotein

  2024-06-22

  

  The putative 55-residue apelin proprotein (proapelin or apelin-55) is processed from a 77-residue preproprotein through removal of a 22-residue signal peptide (Table 1). Apelin-55 is further processed into bioactive isoforms of 36, 17, or 13 residues, likely through protease-mediated mechanisms. To

• PNU 37883 hydrochloride AP was originally described as a het

  2024-06-22

  

  AP-1 was originally described as a heterodimer of the bZIP proteins c-Jun and c-Fos. The experiments described here showed that stimulation of TRPV1 channels induced the expression of both of these classical constituents of AP-1. The essential role of both proteins was analyzed in a series of experi

• HMGA proteins have also been linked to localized

  2024-06-22

  

  HMGA proteins have also been linked to localized changes in chromatin/nucleosome structure and alterations of cellular phenotype during induction of gene transcription in activated T lymphocytes. An adaptive immune response is initiated when naïve resting T lymphocytes encounter their corresponding

15058 records 129/1004 page Previous Next First page 上5页 126127128129130 下5页 Last page